产品名称

英文名称：Plasma Amine Oxidase from bovine plasma

同义词

SSAO;Amine oxidase(copper-containing);Amineoxygen oxidoreductase(deaminating)、PAO

产品性质

CAS编号：9001-66-5

EC号：232-623-0

PubChem编号：135326050

酶学委员会编号：I.U.B. 1.4.3.21

别名：PAO

英文别名：SSAO;Amine oxidase(copper-containing);Amineoxygen oxidoreductase(deaminating)

规格或纯度：≥17 Tabor units/mg dry weight

英文名称：Plasma Amine Oxidase from bovine plasma

单位定义：1 international unit oxidizes 1µmole of benzylamine per minute at 25°C, pH 7.2.

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：Plasma amine oxidase (PAO) catalyzes the reactionRCH2NH2 + O2 + H2O → RCHO + NH3 + H2O2. Bovine plasma amine oxidase has a molecular weight of 170 kDa and an optimum pH of 6.2 for spermine and 7.2 for spermidine. Amine oxidases are divided into two classes the pyridoxal and copper containing enzyme to which plasma amine oxidase belongs, and the FAD-containing amino oxidases. Natural substrates include catecholamines, tryptamine derivatives and other physiologically active amines. Plasma amine oxidase is used in research requiring nitrogen group transfers. The molecule is composed of two identical polypeptide chains. There are two pyridoxal phosphates and two atoms of Cu+ per molecule. Bovine plasma amine oxidase is inhibited by copper chelating agents, many carboxyl reagents such as cuprizone, hydroxylamine and cyanide. Benzoic acid and benzyl alcohol are both non-competitive inhibitors (KI = 30 and 34mM respectively). The assay for determination of amine oxidases employed at Aladdin is essentially that of Tabor et al., JBC, 208, 645, (1954) with the reaction temperature reduced to 25°C.Plasma amine oxidase (PAO) catalyzes the reactionRCH2NH2 + O2 + H2O → RCHO + NH3 + H2O2. Bovine plasma amine oxidase has a molecular weight of 170 kDa and an optimum pH of 6.2 for spermine and 7.2 for spermidine. Amine oxidases are divided into two classes the pyridoxal and copper containing enzyme to which plasma amine oxidase belongs, and the FAD-containing amino oxidases. Natural substrates include catecholamines, tryptamine derivatives and other physiologically active amines. Plasma amine oxidase is used in research requiring nitrogen group transfers. The molecule is composed of two identical polypeptide chains. There are two pyridoxal phosphates and two atoms of Cu+ per molecule. Bovine plasma amine oxidase is inhibited by copper chelating agents, many carboxyl reagents such as cuprizone, hydroxylamine and cyanide. Benzoic acid and benzyl alcohol are both non-competitive inhibitors (KI = 30 and 34mM respectively). The assay for determination of amine oxidases employed at Aladdin is essentially that of Tabor et al., JBC, 208, 645, (1954) with the reaction temperature reduced to 25°C.

WGK Germany：3

PubChem CID：135326050

个人防护装备：Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US)

产品包装