产品名称

英文名称：Adenosine 5'-Triphosphate Disodium Salt Hydrate

同义词

34369-07-8、ATP disodium salt、Adenosine 5'-triphosphate disodium salt hydrate、ATP disodium salt hydrate、disodium;[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-oxidophosphoryl] hydrogen phosphate;hydrate、MFCD0、ATP二钠盐水合物、腺苷-5'-三磷酸二钠盐水合物、腺苷-5'-三磷酸二钠盐水合物、ATP 二钠盐

产品性质

CAS编号：34369-07-8

分子式：C10H14N5Na2O13P3·xH2O

分子量：551.14(anhydrous basis)

MDL号：MFCD00150755

PubChem编号：16218877

别名：ATP二钠盐水合物|腺苷-5'-三磷酸二钠盐水合物|腺苷-5'-三磷酸二钠盐水合物|ATP 二钠盐

英文别名：34369-07-8|ATP disodium salt|Adenosine 5'-triphosphate disodium salt hydrate|ATP disodium salt hydrate|disodium;[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-oxidophosphoryl] hydrogen phosphate;hydrate|MFCD0

规格或纯度：99%,用于细胞培养

英文名称：Adenosine 5'-Triphosphate Disodium Salt Hydrate

生化机理：P2 purinergic agonist; increases activity of Ca2+-activated K+ channels; substrate for ATP-dependent enzyme systems

应用：P2 嘌呤能激动剂；增加Ca2+-激活的K+ 通道活性；依赖ATP的酶底物。

储存温度：-20°C储存,充氩

运输条件：超低温冰袋运输

产品介绍：Adenosine 5'-Triphosphate, disodium salt is a p2 purinergic (P2X and P2Y) agonist that increases Ca2+-activated K+ channel activity. It has been found to induce a release of prostoglandin D2 and histamine from rat peritoneal mast cells in a dose-dependent manner.P2 嘌呤能激动剂；增加Ca2+-激活的K+ 通道活性；依赖ATP的酶底物。applicationAdenosine 5′-triphosphate disodium salt hydrate has been usedas a component of transfection mix for the transformation of CRISPR/Cas9 plasmid in parasitesin inflammasome activation assays in bone marrow derived macrophagesfor the stimulation of macrophagesin nucleotide synthesisproduct descriptionAdenosine 5′-triphosphate (ATP) is essential for biological processes including neurotransmission, signal transduction, muscle contraction and cardiac function. ATP is the major energy potential for living systems. They are released from cells under stress and play a key role in immune response. ATP release from injured neurons and consequent breakdown leads to generation of adenosine. ATP may serve as a therapeutic option in anaesthesia and intensive care medicine for the management of pain. Elevated ATP levels are indicative of cell damage and inflammation.

PubChem SID：488199328

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488199328

IUPAC Name：disodium;[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-oxidophosphoryl] hydrogen phosphate;hydrate

INCHI：InChI=1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1

InChi Key：NTBQNWBHIXNPRU-MSQVLRTGSA-L

Canonical SMILES：C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)([O-])OP(=O)(O)[O-])O)O)N.O.[Na+].[Na+]

Isomeric SMILES：C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(O)OP(=O)([O-])OP(=O)(O)[O-])O)O)N.O.[Na+].[Na+]

WGK Germany：3

关联CAS：987-65-5

PubChem CID：16218877

溶解性：Soluble in water.

密度：2.63

敏感性：对光和热敏感,易吸湿

比旋光度：-19° (C=3,H2O)

Merck Index：155

个人防护装备：Eyeshields, Faceshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

产品包装