产品名称

英文名称：Docetaxel

同义词

Docetaxel [INN]、D07866、NSC 759850、CS-0214895、Lead di(acetate)、NCGC00242509-01、DOCETAXEL MYLAN、Ethanol, 2,2'-iminodi-, 3,5-diiodo-4-oxo-1(4H)-pyridineacetate (salt)、KS-1452、NCGC00181306-01、DB12492、Docetaxel anhydrous、Docetaxol、EmDOC、Q-100074、Taxotere (TN)、多西他赛

产品性质

CAS编号：114977-28-5

分子式：C43H53NO14

分子量：807.88

MDL号：MFCD00800737

PubChem编号：148124

别名：多西他赛

英文别名：Docetaxel [INN]|D07866|NSC 759850|CS-0214895|Lead di(acetate)|NCGC00242509-01|DOCETAXEL MYLAN|Ethanol, 2,2'-iminodi-, 3,5-diiodo-4-oxo-1(4H)-pyridineacetate (salt)|KS-1452|NCGC00181306-01|DB12492|Docetaxel anhydrous|Docetaxol|EmDOC|Q-100074|Taxotere (TN)|

规格或纯度：分析标准品,≥99%

英文名称：Docetaxel

生化机理：多西紫杉醇是与紫杉醇有关联的紫杉烷的抗癌剂。它结合并稳定微管的β-微管蛋白亚基，阻止导致细胞周期阻滞和凋亡的有丝分裂纺锤体的解聚

储存温度：2-8°C储存

运输条件：冰袋运输

产品介绍：Docetaxel(Taxotere), an analog of taxol, is an inhibitor of depolymerisation of microtubules throμgh binding to stabilized microtubules.多西紫杉醇可用于研究抗生素，细胞生物学，细胞信号传导，神经科学,细胞凋亡和细胞周期。Docetaxel(Taxotere), an analog of taxol, is an inhibitor of depolymerisation of microtubules through binding to stabilized microtubules.Docetaxel can be used to study antibiotics, cell biology, cell signaling, neuroscience and apoptosis and the cell cycle.

IUPAC Name：[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1,9,12-trihydroxy-15-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate

INCHI：InChI=1S/C43H53NO14/c1-22-26(55-37(51)32(48)30(24-15-11-9-12-16-24)44-38(52)58-39(3,4)5)20-43(53)35(56-36(50)25-17-13-10-14-18-25)33-41(8,34(49)31(47)29(22)40(43,6)7)27(46)19-28-42(33,21-54-28)57-23(2)45/h9-18,26-28,30-33,35,46-48,53H,19-21H2,1-8H3,(H,44,52)/t26-,27-,28+,30-,31+,32+,33-,35-,41+,42-,43+/m0/s1

InChi Key：ZDZOTLJHXYCWBA-VCVYQWHSSA-N

Canonical SMILES：CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O

Isomeric SMILES：CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1OC(=O)[C@@H]([C@H](C5=CC=CC=C5)NC(=O)OC(C)(C)C)O)O)OC(=O)C6=CC=CC=C6)(CO4)OC(=O)C)O)C)O

WGK Germany：3

RTECS：DA4172750

PubChem CID：148124

密度：1.37

熔点：186-191°C

象形图：

信号词：Danger

危险声明：H319 Causes serious eye irritationH341 Suspected of causing genetic defectsH351 Suspected of causing cancerH372 Causes damage to organs through prolonged or repeated exposureH360 May damage fertility or the unborn childH361 Suspected of damaging fertility or the unborn childH362 May cause harm to breast-fed children

预防措施声明：P305+P351+P338,P280,P405,P501,P264,P260,P281,P270,P263,P203,P264+P265,P318,P337+P317,P319

个人防护装备：Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

产品包装