产品名称

英文名称：Vadadustat

同义词

Vadadustat、1000025-07-9、AKB-6548、PG-1016548、Vadadustat [USAN]、B506、PG1016548、B-506、N-(5-(3-Chlorophenyl)-3-hydroxypyridine-2-carbonyl)glycine、AKB6548、(5-(3-chlorophenyl)-3-hydroxypicolinoyl)glycine、Glycine, N-[[5-(3-chlorophenyl)-3-hydroxy-2-pyridinyl]car

产品性质

CAS编号：1000025-07-9

分子式：C14H11ClN2O4

分子量：306.701

PubChem编号：23634441

英文别名：Vadadustat|1000025-07-9|AKB-6548|PG-1016548|Vadadustat [USAN]|B506|PG1016548|B-506|N-(5-(3-Chlorophenyl)-3-hydroxypyridine-2-carbonyl)glycine|AKB6548|(5-(3-chlorophenyl)-3-hydroxypicolinoyl)glycine|Glycine, N-[[5-(3-chlorophenyl)-3-hydroxy-2-pyridinyl]car

规格或纯度：97%

英文名称：Vadadustat

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：说明Vadadustat (AKB-6548, B-506, PG-1016548)是一种新型的、可用于口服的HIF-PH抑制剂。

ALogP：2.5

IUPAC Name：2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino]acetic acid

INCHI：InChI=1S/C14H11ClN2O4/c15-10-3-1-2-8(4-10)9-5-11(18)13(16-6-9)14(21)17-7-12(19)20/h1-6,18H,7H2,(H,17,21)(H,19,20)

InChi Key：JGRXMPYUTJLTKT-UHFFFAOYSA-N

Canonical SMILES：C1=CC(=CC(=C1)Cl)C2=CC(=C(N=C2)C(=O)NCC(=O)O)O

Isomeric SMILES：C1=CC(=CC(=C1)Cl)C2=CC(=C(N=C2)C(=O)NCC(=O)O)O

PubChem CID：23634441

ChEMBL Ligand：CHEMBL3646221

BindingDB Ligand：107704

DrugBank Ligand：DB12255

RCSB PDB Ligand：A1Z

CAS Registry No.：1000025-07-9

溶解性：insoluble in H2O; ≥57.7 mg/mL in DMSO; ≥9.66 mg/mL in EtOH

象形图：

信号词：Warning

危险声明：H373 Causes damage to organs through prolonged or repeated exposureH302 Harmful if swallowed

预防措施声明：P501,P264,P260,P270,P330,P301+P317,P319

产品包装