产品名称

英文名称：Coenzyme II reduced tetrasodium salt

同义词

2646-71-1、Nadph tetrasodium salt、EINECS 220-163-3、NADPH tetrasodium、Dihydronicotinamide-adenine dinucleotide phosphate, tetrasodium salt、MFCD00036263、A-NADPH、NADPH (sodium salt)、beta-Nicotinamide adenine dinucleotide 2'-phosphate reduced tetrasodium salt、β-NADPH、还原型辅酶Ⅱ四钠盐、还原型β-烟酰胺腺嘌呤二核苷酸 2'-磷酸 四钠盐水合物、2'-NADPH 水合物、还原型三磷酸吡啶核苷酸四钠盐、二氢烟酰胺腺嘌呤二核苷酸磷酸四钠盐、β-烟碱腺嘌呤二核苷磷酸盐四钠盐 (还原型)、β-NADPH四钠盐 (还原型)、TPNH四钠盐 (还原型)、β-三磷酸吡啶二核苷酸四钠盐 (还原型)

产品性质

CAS编号：2646-71-1

分子式：C21H26N7Na4O17P3 · xH2O

分子量：833.35 (anhydrous basis)

MDL号：MFCD00036263

PubChem编号：52945042

别名：β-NADPH|还原型辅酶Ⅱ四钠盐|还原型β-烟酰胺腺嘌呤二核苷酸 2'-磷酸 四钠盐水合物|2'-NADPH 水合物|还原型三磷酸吡啶核苷酸四钠盐|二氢烟酰胺腺嘌呤二核苷酸磷酸四钠盐|β-烟碱腺嘌呤二核苷磷酸盐四钠盐 (还原型)|β-NADPH四钠盐 (还原型)|TPNH四钠盐 (还原型)|β-三磷酸吡啶二核苷酸四钠盐 (还原型)

英文别名：2646-71-1|Nadph tetrasodium salt|EINECS 220-163-3|NADPH tetrasodium|Dihydronicotinamide-adenine dinucleotide phosphate, tetrasodium salt|MFCD00036263||A-NADPH|NADPH (sodium salt)|beta-Nicotinamide adenine dinucleotide 2'-phosphate reduced tetrasodium salt

规格或纯度：95%

英文名称：Coenzyme II reduced tetrasodium salt

生化机理：NADPH, Tetrasodium Salt ia a ubiquitous cofactor and biological reducing agent that acts as an electron donor in many biological reactions. It is generated by reduction of the electron acceptor NADP+, and is very similar to another cofactor, NADH, which lacks a phosphate group at position 2’ of the ribose moiety on the adenine half of the dinucleotide. This compound is involved in many pertinent biochemical pathways, including formation of carbohydrate from CO2 during photosynthesis, maintenance of high levels of reduced glutathione in erythrocytes, reduction of thioredoxin, and formation of free radicals in immune cells which are used to destroy pathogens - aka the respiratory burst.

储存温度：-20°C储存,充氩

运输条件：超低温冰袋运输

产品介绍：β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).通常作为电子供体，是很多氧化还原酶(包括一氧化氮合成酶)的辅酶(cofactor)。β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).A ubiquitous cofactor and biological reducing agent.

IUPAC Name：tetrasodium;[(2R,3R,4R,5R)-2-(6-aminopurin-9-yl)-5-[[[[(2R,3S,4R,5R)-5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl]oxymethyl]-4-hydroxyoxolan-3-yl] phosphate

INCHI：InChI=1S/C21H30N7O17P3.4Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;;;/h1,3-4,7-8,10-11,13-16,20-21,29-31H,2,5-6H2,(H2,23,32)(H,36,37)(H,38,39)(H2,22,24,25)(H2,33,34,35);;;;/q;4*+1/p-4/t10-,11-,13-,14-,15-,16-,20-,21-;;;;/m1..../s1

InChi Key：WYWWVJHQDVCHKF-ITGWJZMWSA-J

Canonical SMILES：C1C=CN(C=C1C(=O)N)C2C(C(C(O2)COP(=O)([O-])OP(=O)([O-])OCC3C(C(C(O3)N4C=NC5=C(N=CN=C54)N)OP(=O)([O-])[O-])O)O)O.[Na+].[Na+].[Na+].[Na+]

Isomeric SMILES：C1C=CN(C=C1C(=O)N)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])OP(=O)([O-])OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)OP(=O)([O-])[O-])O)O)O.[Na+].[Na+].[Na+].[Na+]

PubChem CID：52945042

溶解性：Soluble in water (50 mg/ml).10 mM NaOH soluble 50 mg/mL, clear

密度：2.28

敏感性：对热和空气和光线敏感

Merck Index：6348

产品包装