产品名称

英文名称：HATU

同义词

2-(7-Aza-1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate、O-(7-Azabenzotriazol-1-yl)-N,N,N,N-tetramethyl uronium hexafluorophosphate、MFCD00274639、2-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate、HATU、N-(二甲基氨基)-1H-1,2,3-三唑-4,5-b吡啶-1-亚甲基-N-甲基甲铵六氟磷酸酯- N-氧化物, 1-双(二甲基氨基)亚甲基-1H-1,2,3-三唑4,5-b吡啶-3-氧化物六氟磷酸酯, N,N,N',N'-四甲基-O-(7-氮杂苯并三唑-1-基)六氟磷酸脲、O-(7-氮苯并三氮唑)-N,N,N',N'-四甲基脲六氟磷酸酯、1-[双(二甲氨基)亚甲基]-1H-1,2,3-三唑丙[4,5-b]吡啶3-氧化物六氟磷酸盐

产品性质

CAS编号：148893-10-1

分子式：C10H15F6N6OP

分子量：380.23

MDL号：MFCD00274639

PubChem编号：9886157

别名：HATU|N-(二甲基氨基)-1H-1,2,3-三唑-4,5-b吡啶-1-亚甲基-N-甲基甲铵六氟磷酸酯- N-氧化物, 1-双(二甲基氨基)亚甲基-1H-1,2,3-三唑4,5-b吡啶-3-氧化物六氟磷酸酯, N,N,N',N'-四甲基-O-(7-氮杂苯并三唑-1-基)六氟磷酸脲|O-(7-氮苯并三氮唑)-N,N,N',N'-四甲基脲六氟磷酸酯|1-[双(二甲氨基)亚甲基]-1H-1,2,3-三唑丙[4,5-b]吡啶3-氧化物六氟磷酸盐

英文别名：2-(7-Aza-1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate|O-(7-Azabenzotriazol-1-yl)-N,N,N,N-tetramethyl uronium hexafluorophosphate|MFCD00274639|2-(3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate

规格或纯度：99%

英文名称：HATU

储存温度：2-8°C储存,充氩

运输条件：冰袋运输

产品介绍：用作以下反应的试剂Aurora A激酶抑制剂的合成人血浆中的D-和L-酸对映体的HPLC测定酰胺键形成反应用作以下反应的催化剂选择性酰化反应硒环化-氧化脱硒连续反应通过固相合成制备 N-芳基磺酰胺键合肽。肽偶联剂。HATU is useful as a peptide coupling agent and a catalyst for selective acylation. It is also a reagent for reactions involving amide bond formations.

IUPAC Name：[dimethylamino(triazolo[4,5-b]pyridin-3-yloxy)methylidene]-dimethylazanium;hexafluorophosphate

INCHI：InChI=1S/C10H15N6O.F6P/c1-14(2)10(15(3)4)17-16-9-8(12-13-16)6-5-7-11-9;1-7(2,3,4,5)6/h5-7H,1-4H3;/q+1;-1

InChi Key：JNWBBCNCSMBKNE-UHFFFAOYSA-N

Canonical SMILES：CN(C)C(=[N+](C)C)ON1C2=C(C=CC=N2)N=N1.F[P-](F)(F)(F)(F)F

Isomeric SMILES：CN(C)C(=[N+](C)C)ON1C2=C(C=CC=N2)N=N1.F[P-](F)(F)(F)(F)F

WGK Germany：3

PubChem CID：9886157

Reaxy-Rn：11805773

溶解性：Soluble in Acetone and DMSO

敏感性：对热敏感，易吸潮

熔点：183-186°C

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritationH317 May cause an allergic skin reactionH228 Flammable solid

预防措施声明：P261,P305+P351+P338,P280,P370+P378,P210,P302+P352,P321,P405,P501,P240,P264,P271,P241,P304+P340,P403+P233,P272,P333+P313,P362+P364,P264+P265,P337+P317,P332+P317,P319

个人防护装备：dust mask type N95 (US),Eyeshields,Gloves

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