产品名称

英文名称：7α,25-dihydroxycholesterol

同义词

7alpha,25-Dihydroxycholesterol、64907-22-8、7alpha,25-OHC、Cholest-5-ene-3beta,7alpha,25-triol、7-alpha,25-Dihydroxycholesterol、7alpha,25-Dihydroxyxcholesterol、CHEMBL4788348、7、A,25-dihydroxycholesterol、5-Cholesten-3beta,7alpha,25-triol、3beta,7alpha,25-Trihydr

产品性质

CAS编号：64907-22-8

分子式：C27H46O3

分子量：418.652

PubChem编号：11954197

英文别名：7alpha,25-Dihydroxycholesterol|64907-22-8|7alpha,25-OHC|Cholest-5-ene-3beta,7alpha,25-triol|7-alpha,25-Dihydroxycholesterol|7alpha,25-Dihydroxyxcholesterol|CHEMBL4788348|7|A,25-dihydroxycholesterol|5-Cholesten-3beta,7alpha,25-triol|3beta,7alpha,25-Trihydr

规格或纯度：>98%

英文名称：7α,25-dihydroxycholesterol

生化机理：高效GPR183（EBI2）激动剂（EC50 = 140 pM）和公认的GPR183天然配体。调节体内表达GPR183的B细胞和T细胞的迁移。使B细胞脱敏并减少其对脾滤泡的运动。

储存温度：2-8°C储存

运输条件：冰袋运输

IUPAC Name：(3S,7S,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol

INCHI：InChI=1S/C27H46O3/c1-17(7-6-12-25(2,3)30)20-8-9-21-24-22(11-14-27(20,21)5)26(4)13-10-19(28)15-18(26)16-23(24)29/h16-17,19-24,28-30H,6-15H2,1-5H3/t17-,19+,20-,21+,22+,23-,24+,26+,27-/m1/s1

InChi Key：BQMSKLCEWBSPPY-IKVTXIKFSA-N

Canonical SMILES：CC(CCCC(C)(C)O)C1CCC2C1(CCC3C2C(C=C4C3(CCC(C4)O)C)O)C

Isomeric SMILES：C[C@H](CCCC(C)(C)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@@H](C=C4[C@@]3(CC[C@@H](C4)O)C)O)C

WGK Germany：3

PubChem CID：11954197

CAS Registry No.：64907-22-8

ChEBI：CHEBI37623

RCSB PDB Ligand：KJX

GPCRdb Ligand：7α,25-dihydroxycholesterol

溶解性：溶于DMSO, 最高浓度 (mg/mL) 4.19, 最高浓度(mM) 10 温和加热

产品包装