产品名称

英文名称：Dexpramipexole

同义词

Dexpramipexole [USANINN]、UNII-WI638GUS96、BDBM50568780、F19514、DEXPRAMIPEXOLE [USAN]、(6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine、(6R)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine、(R)-PRAMIPEXOLE、CS-1196、SCHEMBL74780、DTXSID501、(R)-普拉克索

产品性质

CAS编号：104632-28-2

分子式：C10H17N3S

分子量：211.33

PubChem编号：59868

别名：(R)-普拉克索

英文别名：Dexpramipexole [USANINN]|UNII-WI638GUS96|BDBM50568780|F19514|DEXPRAMIPEXOLE [USAN]|(6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine|(6R)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine|(R)-PRAMIPEXOLE|CS-1196|SCHEMBL74780|DTXSID501

规格或纯度：≥98%

英文名称：Dexpramipexole

生化机理：Dexpramipexole, also known as R-(+)-Pramipexole, is a neuroprotective agent and weak non-ergoline dopamine agonist. Dexpramipexole has been found to have neuroprotective effects and is being investigated for treatment of amyotrophic lateral sclerosis (ALS). Dexpramipexole reduces mitochondrial reactive oxygen species (ROS) production, inhibits the activation of apoptotic pathways, and increase cell survival in response to a variety of neurotoxins and β-amyloid neurotoxicity. Compared to the S-(-) isomer, Dexpramipexole has much lower dopamine agonist activity.

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：10mg卖完停产，不再备货

产品介绍：Dexpramipexole(KNS-760704)也叫R-(+)-Pramipexole，是神经保护剂，是弱的非麦角类多巴胺受体激动剂。Dexpramipexole(KNS-760704), also known as R-(+)-Pramipexole, is a neuroprotective agent and weak non-ergoline dopamine agonist

IUPAC Name：(6R)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine

INCHI：InChI=1S/C10H17N3S/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8/h7,12H,2-6H2,1H3,(H2,11,13)/t7-/m1/s1

InChi Key：FASDKYOPVNHBLU-SSDOTTSWSA-N

Canonical SMILES：CCCNC1CCC2=C(C1)SC(=N2)N

Isomeric SMILES：CCCN[C@@H]1CCC2=C(C1)SC(=N2)N

PubChem CID：59868

溶解性：DMSO

产品包装