产品名称

英文名称：L-Carnosine

同义词

beta-Alanyl-L-histidine 、 H-Beta-Ala-His-OH 、 L-Ignotine 、 β-Alanyl-L-histidine、N-β-丙氨酰-L-组氨酸 、 β-丙氨酰-L-组氨酸 、 L-肉缩氨基酸

产品性质

CAS编号：305-84-0

分子式：C9H14N4O3

分子量：226.23

Beilstein号：87671

EC号：206-169-9

MDL号：MFCD00005207

PubChem编号：439224

别名：N-β-丙氨酰-L-组氨酸 | β-丙氨酰-L-组氨酸 | L-肉缩氨基酸

英文别名：beta-Alanyl-L-histidine | H-Beta-Ala-His-OH | L-Ignotine | β-Alanyl-L-histidine

规格或纯度：98%

英文名称：L-Carnosine

生化机理：L-Carosine is a dipeptide found at millimolar concentration in brain, muscle and the lens of the eye. In model systems it is a potent antioxidant that scavenges oxygen free radicals and transition metal ions. It blocks protein-protein and protein-DNA cross-links induced by hypochlorite anions and toxic aldehydes such as acetaldehyde, formaldehyde, and malondialdehyde, the primary product of lipid peroxidation. It also inhibits nonenzymatic protein glycation induced by aldose and ketose reducing sμgars and inhibits the formation of toxic advanced glycation end products (AGE). These activities make it of interest in studies of aging, atherosclerosis, Alzheimer′s disease, and the secondary effects of diabetes.

应用：二肽，具潜在的抗氧剂和抗糖基化活性；阻止乙醛诱导的非酶糖基化和蛋白质偶联。也是肌肽酶检测的底物。具细胞抗氧化，维持机体pH平衡，延长细胞寿命。

储存温度：-20°C储存,充氩

运输条件：超低温冰袋运输

备注：1g卖完停产，不再备货

产品介绍：L-肌肽是一种二肽，以毫摩尔浓度出现在大脑、肌肉和眼睛的晶状体上。二肽，具潜在的抗氧剂和抗糖基化活性；阻止乙醛诱导的非酶糖基化和蛋白质偶联。也是肌肽酶检测的底物。具细胞抗氧化，维持机体pH平衡，延长细胞寿命。Carnosine is an antioxidant. Inhibits soluble guanylyl cyclase (sGC) by interacting with the heme iron to form a chelate complex.An antioxidant soluble guanylyl cyclase inhibitor.

IUPAC Name：(2S)-2-(3-aminopropanoylamino)-3-(1H-imidazol-5-yl)propanoic acid

INCHI：InChI=1S/C9H14N4O3/c10-2-1-8(14)13-7(9(15)16)3-6-4-11-5-12-6/h4-5,7H,1-3,10H2,(H,11,12)(H,13,14)(H,15,16)/t7-/m0/s1

InChi Key：CQOVPNPJLQNMDC-ZETCQYMHSA-N

Canonical SMILES：C1=C(NC=N1)CC(C(=O)O)NC(=O)CCN

Isomeric SMILES：C1=C(NC=N1)C[C@@H](C(=O)O)NC(=O)CCN

WGK Germany：2

RTECS：MS3080000

关联CAS：305-84-0,1370422-07-3

PubChem CID：439224

MeSH Entry Terms：beta Alanylhistidine;beta-Alanylhistidine;Carnosine;Carnosine Hydrochloride;Carnosine, (D-His)-Isomer;Hydrochloride, Carnosine;L Carnosine;L-Carnosine

Reaxy-Rn：87671

ChEBI：CHEBI15727

Wikipedia：Carnosine

CAS Registry No.：305-84-0

ChEMBL Ligand：CHEMBL242948

RCSB PDB Ligand：8V0

溶解性：Soluble in 80% acetic acid (10 mg/ml), and water (13.1).

密度：1.375

敏感性：易吸潮;对空气敏感

比旋光度：21 ° (C=2, H2O)

熔点：253°C

Merck Index：1850

个人防护装备：Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

产品包装