产品名称

英文名称：Heparin sodium salt

同义词

Heparin, sodium salt、PD056845、sodium;2-[3,5-bis(2-hydroxyethyl)-1,3,5-triazinan-1-yl]ethanolate、Heparin sodium salt (MW 15kDa)、D78319、Nadroparin Sodium、肝素

产品性质

CAS编号：9041-08-1

MDL号：MFCD00081689

PubChem编号：118989588

别名：肝素

英文别名：Heparin, sodium salt|PD056845|sodium;2-[3,5-bis(2-hydroxyethyl)-1,3,5-triazinan-1-yl]ethanolate|Heparin sodium salt (MW 15kDa)|D78319|Nadroparin Sodium

规格或纯度：≥180 USP units/mg

英文名称：Heparin sodium salt

生化机理：Heparin, Sodium salt is a low molecular weight heparin (LMWH) polymer that produces its major anticoagulant effect by activating antithrombin. This activation causes a conformational change in ATIII and allows for increased flexibility in its reactive site loop. Heparin is a highly sulfated glycosaminoglycan known for preventing clots. Heparin, Sodium Salt is also an activator of RyR and ATIII.

应用：生化研究，防止凝血酶原转变成凝血酶。

储存温度：2-8°C储存

运输条件：冰袋运输

产品介绍：几乎无臭。无味。为一种天然多糖，取自猪或牛肠粘液或牛肺。有吸湿性。易溶于水(1g溶于20ml水)，溶于盐水溶液，几乎不溶于乙醇、乙醚、丙酮、氯仿和苯。1%的水溶液pH为6.0-7.5。半数致死量(大鼠，静脉)354mg/kg。生化研究，防止凝血酶原转变成凝血酶。A heparin polymer that produces its anticoagulant effect by activating ATIII (antithrombin).

IUPAC Name：sodium;2-[3,5-bis(2-hydroxyethyl)-1,3,5-triazinan-1-yl]ethanolate

INCHI：InChI=1S/C9H20N3O3.Na/c13-4-1-10-7-11(2-5-14)9-12(8-10)3-6-15;/h13-14H,1-9H2;/q-1;+1

InChi Key：YOMTXLQWRQUKAK-UHFFFAOYSA-N

Canonical SMILES：C1N(CN(CN1CCO)CC[O-])CCO.[Na+]

Isomeric SMILES：C1N(CN(CN1CCO)CC[O-])CCO.[Na+]

WGK Germany：2

RTECS：MI0850000

PubChem CID：118989588

DrugBank Ligand：DB06779

CAS Registry No.：9041-08-1

ChEMBL Ligand：CHEMBL1201460

Wikipedia：Dalteparin

PEP：dalteparin

Reactome Reaction：R-HSA-140791, R-HSA-140806, R-HSA-140870, R-HSA-140872

Reactome Drug：R-ALL-9693047

溶解性：Soluble in water (100 mg/ml), DMSO (< 1 mg/ml), and ethanol (< 1 mg/ml).

个人防护装备：Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

产品包装