产品名称

英文名称：Carprofen

同义词

(S)-alpha-Methyl-6-chloro-9H-carbazole-2-acetic acid、9H-Carbazole-2-acetic acid, 6-chloro-.alpha.-methyl-、Rimadyl Chewable Tablets、SPECTRUM1502006、6-Chloro-alpha-methyl-9H-carbazole-2-acetic acid、HMS2234P15、Rimadyl Caplets、5-22-03-00391 (Beilstein Handboo、卡洛芬

产品性质

CAS编号：53716-49-7

分子式：C15H12ClNO2

分子量：273.72

MDL号：MFCD00079028

PubChem编号：2581

别名：卡洛芬

英文别名：(S)-alpha-Methyl-6-chloro-9H-carbazole-2-acetic acid|9H-Carbazole-2-acetic acid, 6-chloro-.alpha.-methyl-|Rimadyl Chewable Tablets|SPECTRUM1502006|6-Chloro-alpha-methyl-9H-carbazole-2-acetic acid|HMS2234P15|Rimadyl Caplets|5-22-03-00391 (Beilstein Handboo

规格或纯度：>98.0%(HPLC)

英文名称：Carprofen

生化机理：Carprofen is a non-steroidal anti-inflammatory drμg (NSAID) that has been found to have antimicrobial activity. Carprofen is primarily used as a veterinary analgesic and anti-inflammatory for arthritis and pain. Its anti-inflammatory activity is due to cyclooxygenase inihbition with selectivity for COX-2 inhibition, while its antimicrobial activity is less certain. Carprofen can kill B. subtilis by permeabilizing its membrane. Other studies have shown carprofen can target the Escherichia coli DNA polymerase III β subunit.Selective COX-2 inhibitor. NSAID. Decreases prostaglandin production. Shows analgesic and antiedemic effects in vivo. Orally active.

运输条件：常规运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。有毒，请参阅SDS以获取更多信息。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Carprofen 抑制犬科COX2，IC50为30 nM。Carprofen inhibits canine COX2 with IC50 of 30 nM.

IUPAC Name：2-(6-chloro-9H-carbazol-2-yl)propanoic acid

INCHI：InChI=1S/C15H12ClNO2/c1-8(15(18)19)9-2-4-11-12-7-10(16)3-5-13(12)17-14(11)6-9/h2-8,17H,1H3,(H,18,19)

InChi Key：PUXBGTOOZJQSKH-UHFFFAOYSA-N

Canonical SMILES：CC(C1=CC2=C(C=C1)C3=C(N2)C=CC(=C3)Cl)C(=O)O

Isomeric SMILES：CC(C1=CC2=C(C=C1)C3=C(N2)C=CC(=C3)Cl)C(=O)O

RTECS：FE3180000

PubChem CID：2581

DrugBank Ligand：DB00821

CAS Registry No.：53716-49-7

ChEMBL Ligand：CHEMBL1316

Wikipedia：Carprofen

DrugCentral Ligand：518

溶解性：可溶于甲醇

熔点：200 °C

象形图：

信号词：Danger

危险声明：H301 Toxic if swallowed

预防措施声明：P321,P405,P501,P264,P270,P330,P301+P316

Merck Index：1862

产品包装