产品名称

英文名称：Disodium 4,4'-Diisothiocyanato -2,2'-stilbenedisulfonate Hydrate

同义词

dids、67483-13-0、DIDS sodium salt、NSC 344481、1VFRQ7416A、MDL-101114ZA、4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid disodium salt、132132-49-1、Disodium 4,4'-diisothiocyano-2,2'-stilbenedisulfonate、4,4'-Diisothiocyanato-2,2'-stilbenedisulfonic Acid Disod

产品性质

CAS编号：67483-13-0

分子式：C16H8N2Na2O6S4

分子量：498.47

MDL号：MFCD00009638

PubChem编号：5702690

英文别名：dids|67483-13-0|DIDS sodium salt|NSC 344481|1VFRQ7416A|MDL-101114ZA|4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid disodium salt|132132-49-1|Disodium 4,4'-diisothiocyano-2,2'-stilbenedisulfonate|4,4'-Diisothiocyanato-2,2'-stilbenedisulfonic Acid Disod

规格或纯度：>90.0%(HPLC)

英文名称：Disodium 4,4'-Diisothiocyanato -2,2'-stilbenedisulfonate Hydrate

生化机理：一种用于细胞转运研究的细胞阴离子渗透性特异性抑制剂。 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid is an anionic alkylating agent containing isothiocyanate residue. It is a negatively charged homobifunctional cross-linking reagent. 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid is a specific inhibitor of cellular anion permeability used in cell transport studies. The isothiocyanate groups react with primary amines at pH 9.0-10.0. 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid alkylates lysine residues and inhibits apoptosis indirectly by targeting membrane based anion transporters.In addition, it also inhibits calcium transport in vesicles.抑制阴离子转运的二苯乙烯二磺酸盐。用于通过质膜定位的Cl-通道抑制Cl-的吸收，以研究氯化物的运输。还有效抑制各种钠耦合的碳酸氢盐转运蛋白。与...反应

应用：Amine-Reactive fluorescent probe 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid disodium salt hydrate has been used · as band3 protein inhibitor in rabbits(19) · for the inhibition of bicarbonate transporters in brain slice tissue(20) · as HCO3-/Cl- exchanger (anion exchanger) in embryos(21)

储存温度：2-8°C储存,充氩

运输条件：冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Amine-Reactive fluorescent probe4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid disodium salt hydrate has been used· as band3 protein inhibitor in rabbits(19)· for the inhibition of bicarbonate transporters in brain slice tissue(20)· as HCO3-/Cl- exchanger (anion exchanger) in embryos(21)Amine-Reactive fluorescent probe4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid disodium salt hydrate has been used· as band3 protein inhibitor in rabbits(19)· for the inhibition of bicarbonate transporters in brain slice tissue(20)· as HCO3-/Cl- exchanger (anion exchanger) in embryos(21)

IUPAC Name：disodium;5-isothiocyanato-2-[(E)-2-(4-isothiocyanato-2-sulfonatophenyl)ethenyl]benzenesulfonate

INCHI：InChI=1S/C16H10N2O6S4.2Na/c19-27(20,21)15-7-13(17-9-25)5-3-11(15)1-2-12-4-6-14(18-10-26)8-16(12)28(22,23)24;;/h1-8H,(H,19,20,21)(H,22,23,24);;/q;2*+1/p-2/b2-1+;;

InChi Key：GEPAYBXVXXBSKP-SEPHDYHBSA-L

Canonical SMILES：C1=CC(=C(C=C1N=C=S)S(=O)(=O)[O-])C=CC2=C(C=C(C=C2)N=C=S)S(=O)(=O)[O-].[Na+].[Na+]

Isomeric SMILES：C1=CC(=C(C=C1N=C=S)S(=O)(=O)[O-])/C=C/C2=C(C=C(C=C2)N=C=S)S(=O)(=O)[O-].[Na+].[Na+]

PubChem CID：5702690

Reaxy-Rn：8179433

敏感性：对湿度敏感; 对光线敏感

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritation

预防措施声明：P305+P351+P338,P280,P302+P352,P321,P264,P362+P364,P264+P265,P337+P317,P332+P317

产品包装