产品名称

英文名称：Fluorescein sodium salt

同义词

黄色8号、酸性黄 73、荧光黄二钠盐、荧光素钠盐

产品性质

CAS编号：518-47-8

分子式：C20H10Na2O5

分子量：376.27

Beilstein号：3833041

EC号：208-253-0

MDL号：MFCD00167039

PubChem编号：9885981

别名：黄色8号|酸性黄 73|荧光黄二钠盐|荧光素钠盐

规格或纯度：AR

英文名称：Fluorescein sodium salt

储存温度：充氩

运输条件：常规运输

产品介绍：无气味,有吸湿性。溶于水， 溶液呈黄红色，并带极强的黄绿色荧光，酸化后消失，中和或碱化后又出现，微溶于乙醇，几乎不溶于氯仿和乙醚。水溶液与血浆等渗。荧光素是一种黄嘌呤染料，是生物学中常用的标记试剂。水溶性荧光染料由于其分子半径小，渗透性和血管灌注研究中得到应用。 以荧光素钠作为荧光示踪剂，用于研究血脑屏障(BBB)和血脊髓屏障(BSCB)在啮齿类动物模型中的通透性。以该染料为探针底物，研究了有机阴离子转运多肽(OATP)介导的肝细胞药物转运。荧光素钠还被应用于光致退色后 原位 溶质通过荧光恢复进入骨内。 荧光素钠盐被用作一种溶质，用于研究微血管渗透性。它已被用作研究血液屏障穿透性的测试分子。Fluorescein is a xanthene dye and is a common labeling agent in biology.Fluorescein sodium salt has been used as a solute to study microvessel permeability.It has been used as a test molecule to study blood barrier penetration.Water soluble fluorescent dye used in permeability and vascular perfusion studies due to its small molecular radius.Sodium fluorescein is used as a fluorescent tracer to study blood-brain barrier (BBB) and blood-spinal cord barrier (BSCB) permeability in rodent models.The dye was used as a probe substrate in the study of organic anion transporting polypeptide (OATP) mediated drug transport in hepatocytes.Sodium fluorescein was also used to monitor in situ solute transportation into bone through fluorescence recovery after photobleaching (FRAP).

PubChem SID：488196398

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488196398

Canonical SMILES：C1=CC=C2C(=C1)C(=O)OC23C4=C(C=C(C=C4)[O-])OC5=C3C=CC(=C5)[O-].[Na+].[Na+]

Isomeric SMILES：C1=CC=C2C(=C1)C(=O)OC23C4=C(C=C(C=C4)[O-])OC5=C3C=CC(=C5)[O-].[Na+].[Na+]

WGK Germany：1

RTECS：LM5425000

PubChem CID：9885981

Reaxy-Rn：4117321

溶解性：Soluble in water at 1mg/ml

密度：1.601

敏感性：对湿度敏感

熔点：320°C

信号词：Warning

危险声明：H319 Causes serious eye irritation

预防措施声明：P305+P351+P338,P280

Merck Index：4159

个人防护装备：Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

产品包装