产品名称

英文名称：Ethyl 4,4,4-trifluoroacetoacetate

同义词

Ethyl 4,4,4-trifluoroacetoacetate、372-31-6、Ethyl 4,4,4-trifluoro-3-oxobutanoate、Ethyl trifluoroacetoacetate、4,4,4-trifluoro-3-oxobutanoic acid ethyl ester、Ethyl (trifluoroacetyl)acetate、Butanoic acid, 4,4,4-trifluoro-3-oxo-, ethyl ester、ETFAA、4,4,4-Triflu、4,4,4-三氟乙酰乙酸乙酯、三氟乙酰乙酸乙酯、ETFAA

产品性质

CAS编号：372-31-6

分子式：C6H7F3O3

分子量：184.11

Beilstein号：608353

EC号：206-750-7

MDL号：MFCD00000424

PubChem编号：67793

别名：4,4,4-三氟乙酰乙酸乙酯|三氟乙酰乙酸乙酯|ETFAA

英文别名：Ethyl 4,4,4-trifluoroacetoacetate|372-31-6|Ethyl 4,4,4-trifluoro-3-oxobutanoate|Ethyl trifluoroacetoacetate|4,4,4-trifluoro-3-oxobutanoic acid ethyl ester|Ethyl (trifluoroacetyl)acetate|Butanoic acid, 4,4,4-trifluoro-3-oxo-, ethyl ester|ETFAA|4,4,4-Triflu

规格或纯度：98%

英文名称：Ethyl 4,4,4-trifluoroacetoacetate

应用：合成含氟杂环医药和农药的重要中间体，有机合成砌块。 Ethyl 4,4,4-trifluoroacetoacetate (ETFAA) is a general reagent to synthesize enantiopure trifluoromethyl-functionalized products. Applications include · Synthesis of (S)- and (R)-α-trifluoromethyl-aspartic acid and α- trifluoromethyl-serine from chiral CF3-oxazolidines, which is derived from ETFAA. · Enantiopure synthesis of trifluoromethyl-β-amino acid derivatives. · Synthesis of (2R)-2-trifluoromethyl-2-carboxyazetidine, (R)- and (S)-trifluoromethylhomoserines from oxazolidine intermediate obtained by condensing (R)-phenylglycinol with ETFAA.

储存温度：充氩

运输条件：常规运输

产品介绍：溶于乙醇、醚、苯等溶剂。水中溶解度10 g/l (20°C)。合成含氟杂环医药和农药的重要中间体，有机合成砌块。Ethyl 4,4,4-trifluoroacetoacetate (ETFAA) is a general reagent to synthesize enantiopure trifluoromethyl-functionalized products. Applications include• Synthesis of (S)- and (R)-α-trifluoromethyl-aspartic acid and α- trifluoromethyl-serine from chiral CF3-oxazolidines, which is derived from ETFAA.• Enantiopure synthesis of trifluoromethyl-β-amino acid derivatives.• Synthesis of (2R)-2-trifluoromethyl-2-carboxyazetidine, (R)- and (S)-trifluoromethylhomoserines from oxazolidine intermediate obtained by condensing (R)-phenylglycinol with ETFAA.Ethyl 4,4,4-trifluoroacetoacetate (ETFAA) is a general reagent to synthesize enantiopure trifluoromethyl-functionalized products. Applications include• Synthesis of (S)- and (R)-α-trifluoromethyl-aspartic acid and α- trifluoromethyl-serine from chiral CF3-oxazolidines, which is derived from ETFAA.• Enantiopure synthesis of trifluoromethyl-β-amino acid derivatives.• Synthesis of (2R)-2-trifluoromethyl-2-carboxyazetidine, (R)- and (S)-trifluoromethylhomoserines from oxazolidine intermediate obtained by condensing (R)-phenylglycinol with ETFAA.

PubChem SID：488184012

IUPAC Name：ethyl 4,4,4-trifluoro-3-oxobutanoate

INCHI：InChI=1S/C6H7F3O3/c1-2-12-5(11)3-4(10)6(7,8)9/h2-3H2,1H3

InChi Key：OCJKUQIPRNZDTK-UHFFFAOYSA-N

Canonical SMILES：CCOC(=O)CC(=O)C(F)(F)F

Isomeric SMILES：CCOC(=O)CC(=O)C(F)(F)F

WGK Germany：2

PubChem CID：67793

UN Number：3272

Reaxy-Rn：608353

溶解性：Miscible with water, ethanol, benzene and organic solvents.

密度：1.259

折光率：1.375-1.378

闪点(℉)：100.4 °F

闪点(℃)：38℃

沸点：129-130°C

熔点：-39°C

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH412 Harmful to aquatic life with long lasting effectsH302 Harmful if swallowedH226 Flammable liquid and vapor

预防措施声明：P273,P280,P370+P378,P210,P302+P352,P321,P501,P233,P240,P264,P403+P235,P303+P361+P353,P241,P270,P362+P364,P330,P242,P243,P301+P317,P332+P317

个人防护装备：Eyeshields,Faceshields,full-face respirator (US),Gloves,multi-purpose combination respirator cartridge (US),type ABEK (EN14387) respirator filter

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