产品名称

英文名称：7β-Hydroxycholesterol

同义词

7beta-Hydroxycholesterol、566-27-8、(3beta,7beta)-Cholest-5-ene-3,7-diol、5-cholestene-3beta,7beta-diol、7beta-Hydroxy Cholesterol、7-HYDROXYCHOLESTEROL、CHEBI42989、cholest-5-ene-3beta,7beta-diol、7-Hydroxycholesterol, (7beta)-、7.beta.-Hydroxycholesterol、7、A-hy、7β-羟基胆固醇、5--胆甾烯-3β,7β-二醇

产品性质

CAS编号：566-27-8

分子式：C27H46O2

分子量：402.653

PubChem编号：473141

别名：7β-羟基胆固醇|5--胆甾烯-3β,7β-二醇

英文别名：7beta-Hydroxycholesterol|566-27-8|(3beta,7beta)-Cholest-5-ene-3,7-diol|5-cholestene-3beta,7beta-diol|7beta-Hydroxy Cholesterol|7-HYDROXYCHOLESTEROL|CHEBI42989|cholest-5-ene-3beta,7beta-diol|7-Hydroxycholesterol, (7beta)-|7.beta.-Hydroxycholesterol|7|A-hy

规格或纯度：>99%

英文名称：7β-Hydroxycholesterol

生化机理：7β-Hydroxycholesterol is an oxysterol, the enzymatic or non-enzymatic product of cholesterol oxidation. Oxysterols are cytotoxic and induce death in monocytes, smooth muscle cells and endothelial cells. The mechanism of apoptosis induced by oxysterols may involve caspases or DNA fragmentation. Increased levels of 7β-Hydroxycholesterol correlates with increased risk of cardiovascular diseases including atherosclerosis

应用：It was used to study oxysterol-induced apoptosis in human endothelial cells

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：7β-Hydroxy Cholesterol is a metabolite of Cholesterol. Its membrane organizing properties may have implications in Altzheimer’s disease.It was used to study oxysterol-induced apoptosis in human endothelial cells7β-Hydroxy Cholesterol is a metabolite of Cholesterol. Its membrane organizing properties may have implications in Altzheimer’s disease.It was used to study oxysterol-induced apoptosis in human endothelial cells

IUPAC Name：(3S,7R,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol

INCHI：InChI=1S/C27H46O2/c1-17(2)7-6-8-18(3)21-9-10-22-25-23(12-14-27(21,22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h16-18,20-25,28-29H,6-15H2,1-5H3/t18-,20+,21-,22+,23+,24+,25+,26+,27-/m1/s1

InChi Key：OYXZMSRRJOYLLO-KGZHIOMZSA-N

Canonical SMILES：CC(C)CCCC(C)C1CCC2C1(CCC3C2C(C=C4C3(CCC(C4)O)C)O)C

Isomeric SMILES：C[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@H](C=C4[C@@]3(CC[C@@H](C4)O)C)O)C

WGK Germany：3

PubChem CID：473141

CAS Registry No.：566-27-8

ChEBI：CHEBI42989

ChEMBL Ligand：CHEMBL497834

RCSB PDB Ligand：HCR

GPCRdb Ligand：7β-hydroxycholesterol

溶解性：Soluble in Chloroform and Methanol

敏感性：对湿度敏感

产品包装