产品名称

英文名称：Nicardipine hydrochloride

同义词

NICARDIPINE HYDROCHLORIDE、54527-84-3、Nicardipine HCl、Cardene、Perdipine、Nicodel、Loxen、Perdipina、YC-93、Angioglebil、Bionicard、Nicardil、Vasonase、Dafil、Nicardipine (Hydrochloride)、Dagan、Barizin、Cardepine、Dacarel、Lecibra、Lecibral、Lescodil、Nerdipina、Nicapress、Ni、盐酸诺拉替坦

产品性质

CAS编号：54527-84-3

分子式：C26H29N3O6·HCl

分子量：515.99

EC号：259-198-4

MDL号：MFCD00057327

PubChem编号：41114

别名：盐酸诺拉替坦

英文别名：NICARDIPINE HYDROCHLORIDE|54527-84-3|Nicardipine HCl|Cardene|Perdipine|Nicodel|Loxen|Perdipina|YC-93|Angioglebil|Bionicard|Nicardil|Vasonase|Dafil|Nicardipine (Hydrochloride)|Dagan|Barizin|Cardepine|Dacarel|Lecibra|Lecibral|Lescodil|Nerdipina|Nicapress|Ni

规格或纯度：≥98%

英文名称：Nicardipine hydrochloride

生化机理：选择性L型Ca 2+通道阻滞剂（IC 50 = 24.1μM）。二氢吡啶衍生物。有力的冠状动脉和脑血管扩张剂。

储存温度：2-8°C储存

运输条件：冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。有毒，请参阅SDS以获取更多信息。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Nicardipine hydrochloride is the hydrochloride salt preparation of Nicardipine and a potent L-type calcium channel protein inhibitor. Nicardipine is described to alter cytochrome P-450 3A expression throμgh induction of CYP3A. Nicardipine blockade of Ca2+ channels has been correlated to antihypertensive effects.强效钙通道蛋白抑制剂.Nicardipine hydrochloride is the hydrochloride salt preparation of Nicardipine and a potent L-type calcium channel protein inhibitor. Nicardipine is described to alter cytochrome P-450 3A expression through induction of CYP3A. Nicardipine blockade of Ca2+ channels has been correlated to antihypertensive effects.A potent calcium channel protein inhibitor

PubChem SID：488183327

IUPAC Name：5-O-[2-[benzyl(methyl)amino]ethyl] 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;hydrochloride

INCHI：InChI=1S/C26H29N3O6.ClH/c1-17-22(25(30)34-4)24(20-11-8-12-21(15-20)29(32)33)23(18(2)27-17)26(31)35-14-13-28(3)16-19-9-6-5-7-10-19;/h5-12,15,24,27H,13-14,16H2,1-4H3;1H

InChi Key：AIKVCUNQWYTVTO-UHFFFAOYSA-N

Canonical SMILES：CC1=C(C(C(=C(N1)C)C(=O)OCCN(C)CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OC.Cl

Isomeric SMILES：CC1=C(C(C(=C(N1)C)C(=O)OCCN(C)CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OC.Cl

WGK Germany：3

RTECS：US7972100

PubChem CID：41114

溶解性：Soluble in DMSO (1 mg/ml), water (slightly), methanol (50 mg/ml), chloroform (slightly), and 100% ethanol (slightly).

敏感性：对光敏感

象形图：

信号词：Danger

危险声明：H301 Toxic if swallowedH311 Toxic in contact with skinH331 Toxic if inhaled

预防措施声明：P261,P280,P302+P352,P321,P405,P501,P264,P271,P270,P304+P340,P403+P233,P330,P361+P364,P301+P316,P316

Merck Index：6495

个人防护装备：Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

产品包装