产品名称

英文名称：N-Oleoylethanolamine

同义词

n-oleoylethanolamine、oleoylethanolamide、111-58-0、N-(2-Hydroxyethyl)oleamide、Oleylethanolamide、Oleamide MEA、N-oleoyl ethanolamine、Oleoyl Ethanolamide、Oleoyl monoethanolamide、(Z)-N-(2-hydroxyethyl)octadec-9-enamide、N-oleoylethanolamide、OLEIC MONOETHANOLAMID、N-(顺式-9-十八碳烯酰基)乙醇胺、油酰乙醇胺、OEA、N-油酰乙醇胺、N-(2-羟乙基)油酰胺、(9Z)-N-(2-羟乙基)-9-十八烯酰胺、N-(羟乙基)油酰胺

产品性质

CAS编号：111-58-0

分子式：C20H39NO2

分子量：325.529

EC号：203-884-8

MDL号：MFCD00045972

PubChem编号：5283454

别名：N-(顺式-9-十八碳烯酰基)乙醇胺|油酰乙醇胺|OEA|N-油酰乙醇胺|N-(2-羟乙基)油酰胺|(9Z)-N-(2-羟乙基)-9-十八烯酰胺|N-(羟乙基)油酰胺

英文别名：n-oleoylethanolamine|oleoylethanolamide|111-58-0|N-(2-Hydroxyethyl)oleamide|Oleylethanolamide|Oleamide MEA|N-oleoyl ethanolamine|Oleoyl Ethanolamide|Oleoyl monoethanolamide|(Z)-N-(2-hydroxyethyl)octadec-9-enamide|N-oleoylethanolamide|OLEIC MONOETHANOLAMID

规格或纯度：95%

英文名称：N-Oleoylethanolamine

生化机理：Oleoylethanolamide (OEA) is a lipid mediator, which helps to control various biological functions, like food intake. It modulates the gene expression in the small intestine. OEA has the ability to initiate several receptors, such as cannabinoid receptor type 1 (CB1), peroxisome proliferator-activated receptors (PPARs) and G protein-coupled receptor 119 (GPR119). Peroxisome proliferator-activator receptor α (PPARα) agonist .Potent PPAR-α agonist (EC 50 = 120 nM). Anandamide analog. Binds to cannabinoid receptor GPR119. Shows anti-ischemic and neuroprotective effects in vivo. Orally active.

应用：N-Oleoylethanolamine has been used to study its effects on glucagon-like peptide (GLP)-1RA-mediated anorectic signaling and weight loss.

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Oleoylethanolamide (OEA) is an endogenous fatty acid ethanolamine.Small intestine cells, adipose tissues, neurons and astrocytes produces OEA. Oleoylethanolamide (OEA) is an endogenous fatty acid ethanolamine.Small intestine cells, adipose tissues, neurons and astrocytes produces OEA.

IUPAC Name：(Z)-N-(2-hydroxyethyl)octadec-9-enamide

INCHI：InChI=1S/C20H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)21-18-19-22/h9-10,22H,2-8,11-19H2,1H3,(H,21,23)/b10-9-

InChi Key：BOWVQLFMWHZBEF-KTKRTIGZSA-N

Canonical SMILES：CCCCCCCCC=CCCCCCCCC(=O)NCCO

Isomeric SMILES：CCCCCCCC/C=C\CCCCCCCC(=O)NCCO

WGK Germany：3

PubChem CID：5283454

ChEMBL Ligand：CHEMBL280065

BindingDB Ligand：29080

Wikipedia：Oleoylethanolamide

CAS Registry No.：111-58-0

RCSB PDB Ligand：5YM

GPCRdb Ligand：N-oleoylethanolamide

熔点：64 °C

象形图：

信号词：Danger

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritationH318 Causes serious eye damage

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P362+P364,P264+P265,P305+P354+P338,P317,P337+P317,P332+P317,P319

个人防护装备：dust mask type N95 (US), Eyeshields, Gloves

产品包装