产品名称

英文名称：p-Toluenesulfonylmethyl isocyanide

同义词

Tosylmethyl isocyanide、36635-61-7、TosMIC、p-Toluenesulfonylmethyl isocyanide、1-((Isocyanomethyl)sulfonyl)-4-methylbenzene、1-(isocyanomethylsulfonyl)-4-methylbenzene、4-Toluenesulphonylmethyl Isocyanide、4-Toluenesulfonylmethyl isocyanide、Tosylmethylisocyanid、对甲苯磺酰甲基异腈、对甲基苯磺酰甲基异腈、4-甲基苯磺酰甲基异腈、N-对甲苯磺酰甘氨

产品性质

CAS编号：36635-61-7

分子式：CH3C6H4SO2CH2NC

分子量：195.24

Beilstein号：3592382

EC号：253-140-1

MDL号：MFCD00000005

PubChem编号：161915

别名：对甲苯磺酰甲基异腈|对甲基苯磺酰甲基异腈|4-甲基苯磺酰甲基异腈|N-对甲苯磺酰甘氨

英文别名：Tosylmethyl isocyanide|36635-61-7|TosMIC|p-Toluenesulfonylmethyl isocyanide|1-((Isocyanomethyl)sulfonyl)-4-methylbenzene|1-(isocyanomethylsulfonyl)-4-methylbenzene|4-Toluenesulphonylmethyl Isocyanide|4-Toluenesulfonylmethyl isocyanide|Tosylmethylisocyanid

规格或纯度：98%

英文名称：p-Toluenesulfonylmethyl isocyanide

储存温度：2-8°C储存,充氩

运输条件：冰袋运输

产品介绍：产品介绍对甲苯磺酰甲基异腈在微波辐射下与固定化亚胺进行碱促进的1,3-偶极环加成反应，得到1,5-二取代咪唑。它是有机化学中的多功能合成子，广泛用于杂环化合物的合成。用途对甲基苯磺酰甲基异腈用于具有1,3,5-三氧杂环己烷骨架的三联体药物的合成中用作制备生物活性吡咯和咪唑的试剂用作使用糖衍生醛的非对映选择性雀形目反应中的异腈组分Product Introductionp-Toluenesulfonylmethyl isocyanide undergoes base-promoted 1,3-dipolar cycloaddition reaction with immobilized imines under microwave irradiation to yield 1,5-disubstituted imidazoles. It is a versatile synthon in organic chemistry, extensively used for the synthesis of heterocyclic compounds.Applicationp-Toluenesulfonylmethyl isocyanide was usedin the synthesis of triplet drugs with the 1,3,5-trioxazatriquinane skeletonas reagent in the preparation of biologically active pyrroles and imidazolesas the isonitrile component in a diastereoselective Passerini reaction employing sugar-derived aldehydes

IUPAC Name：1-(isocyanomethylsulfonyl)-4-methylbenzene

INCHI：InChI=1S/C9H9NO2S/c1-8-3-5-9(6-4-8)13(11,12)7-10-2/h3-6H,7H2,1H3

InChi Key：CFOAUYCPAUGDFF-UHFFFAOYSA-N

Canonical SMILES：CC1=CC=C(C=C1)S(=O)(=O)C[N+]#[C-]

Isomeric SMILES：CC1=CC=C(C=C1)S(=O)(=O)C[N+]#[C-]

WGK Germany：3

PubChem CID：161915

UN Number：2811

Reaxy-Rn：2331606

溶解性：Soluble in chloroform and methanol. Insoluble in water.

敏感性：对湿度、对光、空气敏感

熔点：109-113°C

象形图：

信号词：Danger

危险声明：H301 Toxic if swallowedH311 Toxic in contact with skinH331 Toxic if inhaledH301+H311+H331 Toxic if swallowed, in contact with skin or if inhaled

预防措施声明：P261,P280,P302+P352,P321,P405,P501,P264,P271,P270,P304+P340,P403+P233,P330,P361+P364,P301+P316,P316

Merck Index：9556

个人防护装备：Eyeshields,Faceshields,Gloves,type P2 (EN 143) respirator cartridges

产品包装